Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987771 | 1.00 | LMNA (0.46) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL11478420 | 0.85 | GABRA1 (0.43) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL11437736 | 0.85 | GABRA1 (0.43) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL1573058 | 0.84 | LMNA (0.48) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL1573057 | 0.84 | LMNA (0.48) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL8987705 | 0.84 | CYP1A2 (0.50) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL9987913 | 0.84 | BLM (0.59) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL8987698 | 0.84 | CYP1A2 (0.50) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL9987916 | 0.84 | BLM (0.59) | LMNAMAPK1BLMNPSR1TSHR | |
| SCHEMBL3838242 | 0.82 | BLM (0.45) | LMNAMAPK1BLMNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591102-B1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| US-5488117-A | FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0545861-B1 | Diphenylacetic acid derivatives as stabilisers for organic material | CIBA GEIGY AG (CH) | 1995-12-27 | — | — | EP | disclosed |
| US-5428162-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| US-5369159-A | Heat, oxidation and radiation resistance for polymers | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
| US-5367008-A | 3-(alkoxyphenyl)benzofuran-2-ones as stabilisers | CIBA-GEIGY CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| CN-1087906-A | 3-(2-acyloxyethoxyphenyl) benzofuran-2-ones as stabilisers | CIBA GEIGY AG (CH) | 1994-06-15 | — | — | CN | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |
| US-5260430-A | Stabilizers for organic materials against oxidative, thermal and light degradation | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0545861-A2 | Diphenylacetic acid derivatives as stabilisers for organic material | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5216052-A | Useful for stabilization of synthetic polymers against oxidative, thermal and light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0146269-B1 | HETERO-POLYCYCLIC AROMATIC COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-03 | — | — | EP | disclosed |
| US-4650882-A | Dyes having two 5-membered lactone rings fused to a central cyclohexa-1.4-diene nucleus | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-17 | — | — | US | disclosed |
| EP-0146269-A2 | Hetero-polycyclic aromatic compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-26 | — | — | EP | disclosed |
| EP-0005779-B1 | PROCESS FOR THE PREPARATION OF ARYLGLYOXYLIC ACIDS | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |
| EP-0005779-A2 | Process for the preparation of arylglyoxylic acids | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |