Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090129 | 0.90 | ALDH1A1 (0.34) | SPHK1SPHK2NPC1RAB9AALDH1A1 | |
| SCHEMBL8091500 | 0.88 | NPC1 (0.45) | SPHK1NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL8090161 | 0.86 | SPHK1 (0.33) | SPHK1SPHK2 | |
| SCHEMBL8083447 | 0.85 | SPHK1 (0.33) | SPHK1SPHK2 | |
| SCHEMBL8098085 | 0.84 | SPHK1 (0.33) | SPHK1SPHK2NPC1RAB9AHPGD | |
| SCHEMBL8097998 | 0.83 | SPHK1 (0.35) | SPHK1SPHK2 | |
| SCHEMBL8095242 | 0.82 | SPHK1 (0.32) | SPHK1SPHK2 | |
| SCHEMBL8091585 | 0.79 | SPHK1 (0.31) | SPHK1SPHK2NPC1RAB9A | |
| SCHEMBL8091591 | 0.78 | SPHK1 (0.31) | SPHK1NPC1RAB9A | |
| SCHEMBL8090137 | 0.77 | NPC1 (0.45) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |