SCHEMBL8091526

SCHEMBL8091526

CC(O)CCN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
ACHE P22303 1/20 0.57
ALOX5 P09917 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA9 Q16790 1/20 0.54
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ALDH1A1 P00352 3/20 0.52
POLB P06746 1/20 0.51
PKM P14618 2/20 0.51
KDM4E B2RXH2 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13197084 0.85 ACHE (0.56) MEN1KMT2AACHEALOX5CA12
SCHEMBL8083430 0.84 ALOX5 (0.53) MEN1KMT2AACHEALOX5CA12
SCHEMBL13197086 0.84 ACHE (0.55) MEN1KMT2AACHEALOX5CA12
SCHEMBL13197092 0.83 ACHE (0.54) MEN1KMT2AACHEALOX5CA12
SCHEMBL8090142 0.82 ACHE (0.62) MEN1KMT2AACHEALOX5CA12
SCHEMBL3586091 0.82 POLB (0.62) MEN1KMT2AACHEALOX5CA12
SCHEMBL15494462 0.81 ALOX5 (0.58) MEN1KMT2AACHEALOX5CA12
SCHEMBL1569306 0.80 ACHE (0.60) ACHEALOX5CA12CA1CA2
SCHEMBL6207633 0.79 ALOX5 (0.62) ACHEALOX5CA12CA1CA2
SCHEMBL2210510 0.79 ALOX5 (0.62) MEN1KMT2AACHEALOX5CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1073993-C Process for preparing bis (ether anhydrides) using alkylamine derived bismides having low melting temperatures GEN ELECTRIC (US) 2001-10-31 CN disclosed
EP-1059291-A2 Process for preparing bis(ether anhydrides) GENERAL ELECTRIC COMPANY (US) 2000-12-13 EP disclosed
US-6008374-A REACTING N-ALKYL NITROPHTHALIMIDE AND A BISPHENOL ALKALI METAL SALT TO FORM BISIMIDE, EXTRACTING THE FORMED BISIMIDE GENERAL ELECTRIC COMPANY (US) 1999-12-28 US disclosed
US-5936099-A N-ALKYL PHTHALAMIDES BY REACTING LIQUID (C3-C6)ALKYLAMINES AND PHTHALIC ANHYDRIDE; NITRATION FOLLOWED BY REACTING WITH A BISPHENOL A; EXCHANGE REACTION TO FORM DIANHYDRIDE; HYDROLYSIS TO PRODUCE TETRACID MONOMER FOR POLYETHERIMIDES GENERAL ELECTRIC CO. (US) 1999-08-10 US disclosed
US-5719295-A FROM N-ALKYL NITROPHTHALAMIDE GENERAL ELECTRIC COMPANY (US) 1998-02-17 US disclosed
US-5536846-A NITRATION, PURIFICATION, LIQUID EXTRACTION, DRYING AND PURIFICATION THEN REACTION WITH ALKALI METAL BISPHENOL AND TRANSFORMATION GENERAL ELECTRIC COMPANY (US) 1996-07-16 US disclosed
CN-1121514-A Process for preparing bis (ether anhydrides) using alkylamine derived bismides having low melting temperatures GEN ELECTRIC (US) 1996-05-01 CN disclosed
EP-0684232-A1 Process for preparing bis(ether anhydrides) GENERAL ELECTRIC COMPANY (US) 1995-11-29 EP disclosed