Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454008 | 0.83 | TDP1 (0.42) | TDP1SMN1; SMN2HTR2ASLC6A4KCNH2 | |
| SCHEMBL10153872 | 0.82 | TDP1 (0.62) | TDP1SMN1; SMN2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8534164 | 0.78 | TDP1 (0.58) | TDP1SMN1; SMN2HTR2ASLC6A4KCNH2 | |
| SCHEMBL10359371 | 0.78 | TDP1 (0.63) | TDP1SMN1; SMN2KMT2AL3MBTL1LMNA | |
| SCHEMBL10553436 | 0.78 | SMN1; SMN2 (0.57) | TDP1SMN1; SMN2KMT2AL3MBTL1LMNA | |
| SCHEMBL11444961 | 0.78 | TDP1 (0.53) | TDP1SMN1; SMN2HTR2ASLC6A4KCNH2 | |
| SCHEMBL2142119 | 0.76 | TDP1 (0.55) | TDP1SMN1; SMN2KMT2AL3MBTL1LMNA | |
| SCHEMBL19122983 | 0.75 | SMN1; SMN2 (0.59) | TDP1SMN1; SMN2KMT2AL3MBTL1MAPT | |
| SCHEMBL11577753 | 0.75 | ACHE (0.46) | TDP1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL7651909 | 0.75 | TAAR1 (0.44) | SMN1; SMN2HTR2AKMT2AGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874805-B1 | PHENYLACETAMIDE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2000-09-20 | — | — | EP | disclosed |
| US-5973201-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-10-26 | — | — | US | disclosed |