SCHEMBL454008

SCHEMBL454008

Cc1ccc(OC(C)N)cc1OC(C)N

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
HTR2A P28223 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SLC6A4 P31645 1/20 0.33
KCNH2 Q12809 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PARP10 Q53GL7 1/20 0.32
CYP2D6 P10635 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA1A P35348 1/20 0.32
MAPT P10636 1/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2902182 0.86 AGXT (0.37) TDP1SMN1; SMN2
SCHEMBL8091598 0.83 TDP1 (0.58) TDP1SMN1; SMN2LMNAHTR2AALDH1A1
SCHEMBL12180740 0.79 ALDH1A1 (0.46) TDP1LMNAALDH1A1KDM4EHPGD
SCHEMBL12180428 0.73 MEN1 (0.44) TDP1SMN1; SMN2LMNAALDH1A1KDM4E
SCHEMBL12697241 0.73 ALDH1A1 (0.41) TDP1SMN1; SMN2LMNAALDH1A1KDM4E
SCHEMBL6495128 0.72 SCN4A (0.47) SMN1; SMN2LMNAHTR2ASLC6A4KCNH2
SCHEMBL12180487 0.72 CA12 (0.48) HTR2AALDH1A1CYP2D6ADRA2AADRA1A
SCHEMBL8282093 0.72 CA12 (0.43) TDP1LMNAALDH1A1KDM4EHPGD
SCHEMBL11577753 0.72 ACHE (0.46) TDP1LMNAALDH1A1PARP10MAPT
SCHEMBL7651909 0.72 TAAR1 (0.44) SMN1; SMN2HTR2AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0852135-B2 Oxidative dyeing composition for keratin fibres and dyeing method employing it OREAL (FR) 2008-03-19 EP claimed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
EP-2613760-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS Segetis, Inc. (US) 2013-07-17 EP disclosed
WO-2012033813-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS SEGETIS, INC. (US) 2012-03-15 WO disclosed
WO-2008102310-A1 DYES FOR KERATINIC FIBERS COMPRISING A SPECIAL ANIONIC THICKENER THE PROCTER & GAMBLE COMPANY (US) 2008-08-28 WO disclosed
EP-1919440-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER The Procter and Gamble Company (US) 2008-05-14 EP disclosed
EP-1888023-A1 COLORANTS FOR KERATIN FIBERS Wella Aktiengesellschaft (DE) 2008-02-20 EP disclosed
EP-1846361-A2 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 2007-10-24 EP disclosed
EP-1841507-A1 AGENTS FOR COLORING KERATIN FIBERS Wella Aktiengesellschaft (DE) 2007-10-10 EP disclosed
WO-2007093943-A1 COLORING AGENTS FOR KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2007-08-23 WO disclosed
WO-2007093954-A1 DYE-CONTAINING PELLETS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2007-08-23 WO disclosed
WO-2007026328-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
WO-2007026313-A2 4-AMINOPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
WO-2007026312-A1 1,3-DIAMINOBENZENE DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
WO-2007010463-A2 2-AMINO-5-AMINOMETHYL-PHENOL DERIVATIVES AND AGENT FOR COLORING KERATIN FIBERS COMPRISING THESE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2007-01-25 WO disclosed
WO-2006130373-A1 COLORANTS FOR KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2006-12-07 WO disclosed
WO-2006086374-A2 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2006-08-17 WO disclosed
WO-2006081245-A1 AGENTS FOR COLORING KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2006-08-03 WO disclosed
EP-1200052-A2 DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP L'OREAL (FR) 2002-05-02 EP disclosed
WO-2001068043-A2 DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP L'OREAL (FR) 2001-09-20 WO disclosed