Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359371 | 0.82 | TDP1 (0.63) | TDP1SMN1; SMN2MAPTNPY1RNPY2R | |
| SCHEMBL8534164 | 0.82 | TDP1 (0.58) | TDP1SMN1; SMN2MAPTNPY1RNPY2R | |
| SCHEMBL8091598 | 0.82 | TDP1 (0.58) | TDP1SMN1; SMN2MAPTNPY1RNPY2R | |
| SCHEMBL16481265 | 0.82 | ALDH1A1 (0.46) | TDP1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL12180740 | 0.82 | ALDH1A1 (0.46) | TDP1MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL9946003 | 0.82 | TDP1 (0.54) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16606251 | 0.82 | ALDH1A1 (0.46) | TDP1MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL11963662 | 0.80 | ALDH1A1 (0.44) | TDP1MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL16756041 | 0.80 | ALDH1A1 (0.46) | TDP1MAPTNPY1RNPY2RALDH1A1 | |
| SCHEMBL3720563 | 0.80 | ALDH1A1 (0.48) | TDP1MAPTNPY1RNPY2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| EP-4253382-A1 | NEW SMALL-MOLECULE COMPOUND FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTOR AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | S&K Therapeutics (KR) | 2023-10-04 | — | — | EP | disclosed |
| US-11693310-B2 | Blue curable resin composition, blue color filter, and display device including same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11693310-B2 | Blue curable resin composition, blue color filter, and display device including same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| US-20230043562-A1 | COLORED RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-02-09 | — | — | US | disclosed |
| US-20200371435-A1 | BLUE CURABLE RESIN COMPOSITION, BLUE COLOR FILTER, AND DISPLAY DEVICE INCLUDING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-3719022-A1 | POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE | Janssen Pharmaceutica NV (BE) | 2020-10-07 | — | — | EP | disclosed |
| EP-3386991-B1 | POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2020-06-03 | — | — | EP | disclosed |
| US-10385070-B2 | Chroman-spirocyclic piperidine amides as modulators of ion channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-08-20 | — | — | US | disclosed |
| WO-2018103060-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE | JANSSEN PHARMACEUTICA NV (BE) | 2018-06-14 | — | — | WO | disclosed |
| US-20090159130-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-06-25 | — | — | US | disclosed |
| US-20090153037-A1 | Novel red electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-06-18 | — | — | US | disclosed |
| US-20090145483-A1 | Novel electroluminescent compounds and organic electroluminescent device suing the same | GRACEL DISPLAY INC. (KR) | 2009-06-11 | — | — | US | disclosed |
| US-20090078317-A1 | Organometalic compounds for electroluminescence and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-03-26 | — | — | US | disclosed |
| US-20090029994-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20080249175-A1 | N-Phenyloxamide derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-10-09 | — | — | US | disclosed |
| US-20080107608-A1 | 5-Substituted-2-Arylpyridines | GE PING | 2008-05-08 | — | — | US | disclosed |
| US-20080015196-A1 | Imidazopyrazines, Imidazopyridines, and Imidazopyrimidines as Crf1 Receptor Ligands | NEUROGEN CORPORATION (US) | 2008-01-17 | — | — | US | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |
| US-7223778-B2 | 5-substituted-2-arylpyridines | NEUROGEN CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249175-A1 | N-Phenyloxamide derivatives | SERPINE1, SERPINH1, F12 | TDP1 2343/4885SMN1; SMN2 3040/4885MAPT 4236/4885 |
| US-20090145483-A1 | Novel electroluminescent compounds and organic electroluminescent device suing the same | LEF1, ODC1, AOC2 | TDP1 2726/4885SMN1; SMN2 3747/4885MAPT 2579/4885 |
| US-20090078317-A1 | Organometalic compounds for electroluminescence and organic electroluminescent device using the same | OCIAD1, L1CAM, OCIAD2 | TDP1 2344/4885SMN1; SMN2 3641/4885MAPT 2039/4885 |
| US-20090153037-A1 | Novel red electroluminescent compounds and organic electroluminescent device using the same | NDUFS2, ALDH1A2, ODC1 | TDP1 2777/4885SMN1; SMN2 4625/4885MAPT 1708/4885 |
| US-20090159130-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | AOX1, LEF1, ODC1 | TDP1 2124/4885SMN1; SMN2 4652/4885MAPT 2613/4885 |
| US-20080015196-A1 | Imidazopyrazines, Imidazopyridines, and Imidazopyrimidines as Crf1 Receptor Ligands | CRHR1, CRHR2, CRHBP | TDP1 1923/4885SMN1; SMN2 811/4885MAPT 3153/4885 |
| US-20090029994-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | TDP1 1348/4885SMN1; SMN2 4864/4885MAPT 2667/4885 |
| US-20080107608-A1 | 5-Substituted-2-Arylpyridines | CRHR2, CRHR1, HTR2C | TDP1 2732/4885SMN1; SMN2 1354/4885MAPT 2953/4885 |
| US-10385070-B2 | Chroman-spirocyclic piperidine amides as modulators of ion channels | KCNJ2, KCNJ1, KCNC1 | TDP1 3694/4885SMN1; SMN2 1515/4885MAPT 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.