Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14631107 | 0.82 | KMT2A (0.41) | MEN1ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL1338876 | 0.75 | CCR8 (0.60) | — | |
| SCHEMBL4425234 | 0.74 | SLC6A2 (0.37) | MEN1ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL532533 | 0.73 | KDM4E (0.46) | MEN1ALDH1A1KMT2AKDM4EESR1 | |
| SCHEMBL28477897 | 0.73 | KMT2A (0.62) | MEN1ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL27768338 | 0.73 | KMT2A (0.58) | MEN1ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3485687 | 0.72 | ALDH1A1 (0.71) | MEN1ALDH1A1KMT2AKDM4ESLC6A4 | |
| Hydrochloric Acid SCHEMBL27714396 | 0.71 | ALDH1A1 (0.69) | MEN1ALDH1A1KMT2AKDM4ESLC6A4 | |
| Hydrochloric Acid SCHEMBL9785714 | 0.71 | ESR1 (0.58) | MEN1ALDH1A1KMT2AKDM4EESR1 | |
| SCHEMBL3839948 | 0.69 | KMT2A (0.41) | MEN1ALDH1A1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |