Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038711 | 0.93 | CES1 (0.44) | BRPF1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL7854100 | 0.89 | MEN1 (0.44) | BRPF1LMNAGAAMEN1KMT2A | |
| SCHEMBL6450576 | 0.85 | BRPF1 (0.44) | BRPF1LMNAGAAMEN1KMT2A | |
| SCHEMBL30277548 | 0.83 | BRPF1 (0.38) | BRPF1LMNAGAAMEN1KMT2A | |
| SCHEMBL14185922 | 0.82 | SLC6A2 (0.53) | BRPF1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9868798 | 0.82 | GRIA2 (0.44) | BRPF1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL19949967 | 0.79 | MEN1 (0.46) | BRPF1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL10680826 | 0.79 | BRPF1 (0.40) | BRPF1LMNAGAAMEN1KMT2A | |
| SCHEMBL9436144 | 0.79 | ALDH1A1 (0.42) | BRPF1LMNAGAAMEN1KMT2A | |
| SCHEMBL28176871 | 0.78 | BRPF1 (0.40) | BRPF1LMNAGAACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103193761-B | 2-phenyl-6-azolylpyridine ligand and group VIII transition metal complex formed by same | JI YUN (CN) | 2015-12-02 | — | — | CN | disclosed |
| US-8889872-B2 | Bisazole-based compound and group VIII transition metal complex | NATIONAL TSING HUA UNIVERSITY (TW) | 2014-11-18 | — | — | US | disclosed |
| US-8580961-B2 | 2-phenyl-6-azolylpyridine-based ligand and group VIII transition metal complex | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-11-12 | — | — | US | disclosed |
| US-20130296567-A1 | BISAZOLE-BASED COMPOUND AND GROUP VIII TRANSITION METAL COMPLEX | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-11-07 | — | — | US | disclosed |
| CN-103193761-A | 2-phenyl-6-azolylpyridine ligand and group VIII transition metal complex formed by same | CHI YUN | 2013-07-10 | — | — | CN | disclosed |
| US-20130018189-A1 | 2-PHENYL-6-AZOLYLPYRIDINE-BASED LIGAND AND GROUP VIII TRANSITION METAL COMPLEX | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-01-17 | — | — | US | disclosed |
| WO-2009035684-A1 | SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS | ACTIVX BIOSCIENCES, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296567-A1 | BISAZOLE-BASED COMPOUND AND GROUP VIII TRANSITION METAL COMPLEX | LAS1L, MLKL, HBS1L | BRPF1 2447/4885LMNA 902/4885GAA 4440/4885 |
| US-20130018189-A1 | 2-PHENYL-6-AZOLYLPYRIDINE-BASED LIGAND AND GROUP VIII TRANSITION METAL COMPLEX | C1S, H1-10, INTS6 | BRPF1 3224/4885LMNA 3649/4885GAA 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.