Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171359 | 0.86 | SERPINE1 (0.39) | SERPINE1LMNAGAAMEN1KMT2A | |
| SCHEMBL8090611 | 0.83 | SERPINE1 (0.55) | SERPINE1LMNAGAAMEN1KMT2A | |
| SCHEMBL8083681 | 0.80 | MAPT (0.41) | SERPINE1LMNAMEN1KMT2AMAPT | |
| SCHEMBL8091948 | 0.80 | SERPINE1 (0.41) | SERPINE1LMNAGAAMEN1KMT2A | |
| SCHEMBL8091901 | 0.79 | LMNA (0.40) | SERPINE1LMNAGAAMEN1KMT2A | |
| SCHEMBL8090679 | 0.79 | MAPT (0.43) | SERPINE1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8606858 | 0.79 | MEN1 (0.39) | SERPINE1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8123521 | 0.79 | SERPINE1 (0.53) | SERPINE1LMNAGAAMEN1KMT2A | |
| SCHEMBL8183707 | 0.79 | CFTR (0.43) | SERPINE1L3MBTL1MAPTALDH1A1POLB | |
| SCHEMBL8091931 | 0.77 | SERPINE1 (0.47) | SERPINE1LMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-0828746-A1 | NOVEL QUINOXALINE DIONE DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037500-A1 | NOVEL QUINOXALINE DIONE DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-11-28 | — | — | WO | disclosed |