Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090680 | 0.87 | SERPINE1 (0.47) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8091881 | 0.85 | MAPT (0.43) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8098486 | 0.84 | AR (0.35) | ALDH1A1KDM4EPTGER4KMT2AHPGD | |
| SCHEMBL8090679 | 0.83 | MAPT (0.43) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8606858 | 0.81 | MEN1 (0.39) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8098464 | 0.80 | ALDH1A1 (0.38) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8083681 | 0.80 | MAPT (0.41) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8171359 | 0.79 | SERPINE1 (0.39) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8091947 | 0.79 | SERPINE1 (0.41) | LMNAALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL8091931 | 0.77 | SERPINE1 (0.47) | LMNAALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |