Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | CTSV | O60911 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083681 | 0.87 | MAPT (0.41) | MAPTMEN1KMT2ACYP19A1SERPINE1 | |
| SCHEMBL8091742 | 0.86 | SERPINE1 (0.52) | MAPTMEN1KMT2ACYP19A1CTSV | |
| SCHEMBL8083649 | 0.85 | S1PR1 (0.37) | MAPTMEN1KMT2AHTR1AADRA1D | |
| SCHEMBL8091901 | 0.83 | LMNA (0.40) | MAPTMEN1KMT2ASERPINE1NPC1 | |
| SCHEMBL8090682 | 0.82 | MAPT (0.42) | MAPTMEN1KMT2ACYP19A1CTSV | |
| SCHEMBL8091881 | 0.81 | MAPT (0.43) | MAPTMEN1KMT2ASERPINE1NPC1 | |
| SCHEMBL8606858 | 0.81 | MEN1 (0.39) | MAPTMEN1KMT2ASERPINE1NPC1 | |
| SCHEMBL8091931 | 0.80 | SERPINE1 (0.47) | MAPTMEN1KMT2ASERPINE1NPC1 | |
| SCHEMBL8171359 | 0.79 | SERPINE1 (0.39) | MAPTMEN1KMT2ASERPINE1RAB9A | |
| SCHEMBL8091947 | 0.79 | SERPINE1 (0.41) | MAPTMEN1KMT2ASERPINE1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |