Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173729 | 0.79 | CA2 (0.55) | PTK2BPOLBNPC1CA2CA4 | |
| SCHEMBL29733396 | 0.79 | CA2 (0.55) | PTK2BPOLBNPC1CA2CA4 | |
| SCHEMBL4956835 | 0.72 | CA2 (0.48) | PTK2BPOLBNPC1CA2CA4 | |
| SCHEMBL8092196 | 0.69 | CA2 (0.33) | PTK2BPOLBNPC1CA2CA4 | |
| SCHEMBL9407116 | 0.66 | CA4 (0.33) | PTK2BPOLBNPC1CA2CA4 | |
| SCHEMBL1227487 | 0.66 | CYP3A4 (0.52) | PTK2BPOLBNPC1CA2CA4 | |
| Potassium Ion SCHEMBL10977992 | 0.65 | GABRA1 (0.40) | PTK2BPOLBNPC1ALDH1A1 | |
| SCHEMBL563975 | 0.65 | POLB (0.47) | PTK2BPOLBNPC1CA2CA4 | |
| Phosphoric Acid SCHEMBL9009498 | 0.65 | SLC34A1 (0.61) | CA2KDM4ECYP2C19 | |
| SCHEMBL11350253 | 0.64 | CYP3A4 (0.50) | PTK2BPOLBNPC1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736539-B1 | Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst | ENITECNOLOGIE SPA (IT) | 2000-12-20 | — | — | EP | disclosed |
| US-5892080-A | Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst | ENIRICERCHE S.P.A. (IT) | 1999-04-06 | — | — | US | disclosed |
| EP-0736539-A2 | Mesoporous crystalline acid composition of a diphosphonate-phosphite of a tetravalent metal which can be used as a catalyst | ENIRICERCHE S.p.A. (IT) | 1996-10-09 | — | — | EP | disclosed |