Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090267 | 0.81 | ALDH1A1 (0.55) | LMNAALDH1A1CA1CA2HSP90AA1 | |
| SCHEMBL10731714 | 0.80 | NPSR1 (0.52) | LMNAL3MBTL1ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL307215 | 0.80 | KMT2A (0.54) | LMNAL3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL9267696 | 0.80 | SMN1; SMN2 (0.50) | LMNAL3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL9270615 | 0.78 | GAA (0.47) | LMNAALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL5175591 | 0.76 | HTT (0.46) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL1760632 | 0.75 | KMT2A (0.58) | LMNAL3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL1537235 | 0.74 | ALDH1A1 (0.58) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL14273119 | 0.74 | FAAH (0.47) | LMNAL3MBTL1ALDH1A1FAAHPHGDH | |
| SCHEMBL4026284 | 0.74 | KMT2A (0.51) | LMNAL3MBTL1ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048296-A1 | DRUGS AUGMENTING NKT CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |