⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809251 | 0.81 | TSHR (0.39) | — | |
| SCHEMBL29782115 | 0.79 | LMNA (0.34) | — | |
| SCHEMBL9897503 | 0.78 | LMNA (0.39) | — | |
| SCHEMBL1597489 | 0.78 | MAPK1 (0.39) | — | |
| SCHEMBL10179034 | 0.78 | SERPINE1 (0.42) | — | |
| SCHEMBL14713276 | 0.78 | CYP4F2 (0.38) | — | |
| SCHEMBL14696063 | 0.78 | CYP2D6 (0.37) | — | |
| SCHEMBL17880642 | 0.76 | — | — | |
| SCHEMBL2022933 | 0.76 | CYP2D6 (0.35) | — | |
| SCHEMBL19239038 | 0.76 | DGAT1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013059137-A1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | OLIGASIS (US) | 2013-04-25 | — | — | WO | disclosed |
| WO-2013059137-A1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | OLIGASIS (US) | 2013-04-25 | — | — | WO | disclosed |
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| EP-1802726-A4 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LTD (AU) | 2008-04-30 | — | — | EP | disclosed |
| EP-1802726-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | Polymers Australia PTY Limited (AU) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006024099-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2006-03-09 | — | — | WO | disclosed |