SCHEMBL8092872

SCHEMBL8092872

Cc1ccc(N)c(Nc2ccc(O)cc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.59
ALDH1A1 P00352 5/20 0.59
ALOX15 P16050 5/20 0.59
THRB P10828 3/20 0.59
CYP3A4 P08684 2/20 0.59
RECQL P46063 2/20 0.59
HIF1A Q16665 1/20 0.59
GAA P10253 7/20 0.53
MAPT P10636 6/20 0.53
KDM4E B2RXH2 5/20 0.49
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
GFER P55789 2/20 0.49
ATM Q13315 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 2/20 0.46
MAPK13 O15264 1/20 0.44
MAPK12 P53778 1/20 0.44
MAPK11 Q15759 1/20 0.44
MAPK14 Q16539 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11647101 0.84 MAPT (0.55) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL11401774 0.82 MAPT (0.53) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL4937983 0.81 MAPT (0.61) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL1623824 0.79 TDP1 (0.46) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL20268378 0.79 MAPT (0.56) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL6029639 0.79 TDP1 (0.64) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL10436762 0.79 TDP1 (0.54) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL11563580 0.78 RAPGEF4 (0.55) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL10494914 0.77 TDP1 (0.57) TDP1ALDH1A1ALOX15THRBCYP3A4
SCHEMBL12786879 0.76 NPSR1 (0.55) TDP1ALDH1A1ALOX15THRBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057916-B Preparation method of lubricating oil antioxidant ashless dispersant 中国石油天然气股份有限公司 2023-11-28 CN claimed
CN-112625777-B Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2022-08-30 CN claimed
CN-114057916-A Preparation method of antioxidant ashless dispersant for lubricating oil 中国石油天然气股份有限公司 2022-02-18 CN claimed
CN-112625777-A Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2021-04-09 CN claimed
CN-114057916-B Preparation method of lubricating oil antioxidant ashless dispersant 中国石油天然气股份有限公司 2023-11-28 CN disclosed
CN-112625777-B Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2022-08-30 CN disclosed
CN-114057916-A Preparation method of antioxidant ashless dispersant for lubricating oil 中国石油天然气股份有限公司 2022-02-18 CN disclosed
CN-112625777-A Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2021-04-09 CN disclosed
EP-0750490-B1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 2000-11-08 EP disclosed
EP-0695163-B1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 1997-03-05 EP disclosed
EP-0695163-A1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 1996-02-07 EP disclosed
WO-1995011001-A1 1,3-PROPANDIONES FOR DYEING KERATINIC FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1995-04-27 WO disclosed
WO-1994024989-A1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-11-10 WO disclosed