SCHEMBL809290

SCHEMBL809290

C=C(CCCC[Si](C)(C)Cl)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.39
TET2 Q6N021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809453 0.83 TBXAS1 (0.41) TBXAS1TET2
SCHEMBL2783362 0.83 TBXAS1 (0.41) TBXAS1TET2
SCHEMBL3820093 0.79 LMNA (0.52)
SCHEMBL2025802 0.78 TBXAS1 (0.47) TBXAS1TET2
SCHEMBL675562 0.77 TBXAS1 (0.37) TBXAS1
SCHEMBL4522220 0.77 TSHR (0.55)
SCHEMBL4530620 0.77 TSHR (0.55)
SCHEMBL4534721 0.77 TSHR (0.55)
SCHEMBL4523031 0.77 TSHR (0.55)
SCHEMBL4536387 0.77 TSHR (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802726-B1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF ADVANCED POLYMERIK PTY LTD (AU) 2011-11-30 EP claimed
WO-2010058148-A1 HYDROPHOBIZED ORGANIC PARTICLE STABILIZED EMULSIONS IMPERIAL INNOVATIONS LTD (GB) 2010-05-27 WO claimed
WO-2010058148-A1 HYDROPHOBIZED ORGANIC PARTICLE STABILIZED EMULSIONS IMPERIAL INNOVATIONS LTD (GB) 2010-05-27 WO disclosed