SCHEMBL809453

SCHEMBL809453

C=C(CCCC[Si](C)(C)C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.41
TET2 Q6N021 4/20 0.33
THRB P10828 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
LMNA P02545 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225184 0.93 TBXAS1 (0.39) TBXAS1TET2TET3TET1GRIK1
SCHEMBL399699 0.84 TET2 (0.37) TBXAS1TET2TET3TET1GRIK1
SCHEMBL809290 0.83 TBXAS1 (0.39) TBXAS1TET2
SCHEMBL2025802 0.81 TBXAS1 (0.47) TBXAS1TET2THRBFNTAFNTB
SCHEMBL675562 0.80 TBXAS1 (0.37) TBXAS1
SCHEMBL442218 0.79 TBXAS1 (0.36) TBXAS1
SCHEMBL400291 0.79 TBXAS1 (0.36) TBXAS1
SCHEMBL442700 0.79 TBXAS1 (0.36) TBXAS1
SCHEMBL2783362 0.78 TBXAS1 (0.41) TBXAS1TET2TET3TET1LMNA
SCHEMBL1860769 0.78 TBXAS1 (0.50) TBXAS1TET2THRBFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784434-B2 IMPLANTABLE DEVICE FROM POLYMERS OF FLUORINATED MONOMERS AND HYDROPHILIC MONOMERS ABBOTT CARDIOVASCULAR SYSTEMS INC (US) 2019-03-13 EP claimed
EP-3224330-B1 INTERNAL POLYMERIC BREAKER FOR VISCOELASTIC SURFACTANT-BASED FLUIDS AKZO NOBEL CHEMICALS INT BV (NL) 2019-02-20 EP claimed
EP-2708584-B1 AMORPHOUS POLY (D,L-LACTIDE) COATING ABBOTT CARDIOVASCULAR SYSTEMS INC (US) 2018-11-14 EP claimed
EP-2316500-B1 Methacrylate copolymers for medical devices ABBOTT CARDIOVASCULAR SYSTEMS (US) 2016-05-11 EP claimed
US-20160074562-A1 DRUG ELUTING STENT WITH A BIODEGRADABLE RELEASE LAYER ATTACHED WITH ELECTRO-GRAFTED PRIMER COATING ALCHIMEDICS (FR) 2016-03-17 US claimed
EP-1879971-B1 AMORPHOUS POLY (D,L-LACTIDE) COATING ABBOTT CARDIOVASCULAR SYSTEMS (US) 2015-11-04 EP claimed
EP-1988873-B1 POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME LUBRIZOL ADVANCED MAT INC (US) 2013-01-09 EP claimed
EP-1802359-B1 METHACRYLATE COPOLYMERS FOR MEDICAL DEVICES ABBOTT CARDIOVASCULAR SYSTEMS (US) 2012-01-11 EP claimed
EP-1833526-B1 POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS ABBOTT CARDIOVASCULAR SYSTEMS (US) 2011-11-09 EP claimed
EP-1784434-B1 POLYMERS OF FLUORINATED MONOMERS AND HYDROPHILIC MONOMERS ABBOTT CARDIOVASCULAR SYSTEMS (US) 2010-03-10 EP claimed
EP-1732621-B1 PHOSPHOLIPID AND NON-FOULING COATING COMPOSITIONS ABBOTT CARDIOVASCULAR SYSTEMS (US) 2009-12-09 EP claimed
EP-0657751-B1 Soft ocular lens material MENICON CO LTD (JP) 2003-04-23 EP claimed
US-5883152-A HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER NIPPON OIL AND FATS CO., LTD. (JP) 1999-03-16 US claimed
JP-3179028-A None JP disclosed
EP-3525722-B1 DRUG ELUTING STENT FOR ENABLING RESTORATION OF FUNCTIONAL ENDOTHELIAL CELL LAYERS SINO MEDICAL SCIENCES TECH INC (CN) 2026-05-06 EP disclosed
US-12509791-B2 Formation of organic electro-grafted films on the surface of electrically conductive or semi-conductive surfaces ALCHIMEDICS (FR) 2025-12-30 US disclosed
EP-0215817-A1 CONTINUOUS-WEAR LENSES. BAUSCH & LOMB (US) 1987-04-01 EP disclosed
EP-0209597-A1 EXTENDED-WEAR LENSES Bausch & Lomb Incorporated (US) 1987-01-28 EP disclosed
WO-1986004343-A1 EXTENDED-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO disclosed
WO-1986004341-A1 CONTINUOUS-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509791-B2 Formation of organic electro-grafted films on the surface of electrically conductive or semi-conductive surfaces HCN4, EPCAM, KCNN4 TBXAS1 4624/4885TET2 346/4885THRB 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.