SCHEMBL8093096

SCHEMBL8093096

Cc1cccc(C(=O)c2ccc(O)c(O)c2O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
KDM4E B2RXH2 3/20 0.61
MAPT P10636 3/20 0.61
HPGD P15428 3/20 0.61
ALDH1A1 P00352 2/20 0.61
ALOX15 P16050 2/20 0.61
RECQL P46063 2/20 0.61
HSD17B10 Q99714 2/20 0.61
MEN1 O00255 2/20 0.61
ALOX12 P18054 1/20 0.61
HDAC1 Q13547 1/20 0.59
POLB P06746 1/20 0.57
CNR2 P34972 2/20 0.49
PARP1 P09874 1/20 0.49
HSD17B14 Q9BPX1 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29215536 0.89 POLB (0.55) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL30996458 0.89 POLB (0.55) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL30669855 0.88 HDAC1 (0.69) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL6842062 0.88 HDAC1 (0.69) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL28507323 0.83 POLB (0.57) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL351277 0.83 HDAC1 (0.62) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL29557325 0.83 HDAC1 (0.62) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL29131799 0.81 HDAC1 (0.53) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL3140072 0.81 POLB (0.62) KMT2AKDM4EMAPTHPGDRECQL
SCHEMBL21783905 0.81 KDM4E (0.58) KMT2AKDM4EMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5563018-A PHOTORESISTS, SHELF LIFE HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-08 US claimed
EP-0563663-B1 1,2-naphtoquinone-2-diazidesulfonic acid esters, a radiation-sensitive composition produced therewith and a radiation-sensitive recording material HOECHST AG (DE) 1995-12-20 EP claimed
EP-0563663-A1 1,2-naphtoquinone-2-diazidesulfonic acid esters, a radiation-sensitive composition produced therewith and a radiation-sensitive recording material HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-06 EP claimed
US-6100004-A RADIATION-SENSITIVE MIXTURE COMPRISING AS AN INFRARED RADIATION ABSORBING COMPONENT A CARBON BLACK PIGMENT HAVING A PRIMARY PARTICLE SIZE SMALLER THAN 80 NM, WHICH IS PREDISPERSED IN A POLYMER CONTAINING ACIDIC UNITS AGFA-GEVAERT N.V. (BE) 2000-08-08 US disclosed
US-5563018-A PHOTORESISTS, SHELF LIFE HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-08 US disclosed
EP-0563663-B1 1,2-naphtoquinone-2-diazidesulfonic acid esters, a radiation-sensitive composition produced therewith and a radiation-sensitive recording material HOECHST AG (DE) 1995-12-20 EP disclosed
EP-0563663-A1 1,2-naphtoquinone-2-diazidesulfonic acid esters, a radiation-sensitive composition produced therewith and a radiation-sensitive recording material HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-06 EP disclosed