Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098007 | 0.89 | CYP4F2 (0.53) | CYP4F2CYP4A11PLK1MAP1LC3BMAP1LC3A | |
| SCHEMBL8095894 | 0.87 | LPL (0.54) | CYP4F2CYP4A11 | |
| SCHEMBL11752450 | 0.86 | KAT6A (0.52) | KAT6ACYP4F2CYP4A11ALOX5MAP1LC3B | |
| SCHEMBL8098026 | 0.86 | LPL (0.55) | CYP4F2CYP4A11 | |
| SCHEMBL8100373 | 0.86 | LPL (0.55) | CYP4F2CYP4A11 | |
| SCHEMBL8087110 | 0.86 | LPL (0.55) | CYP4F2CYP4A11 | |
| SCHEMBL30354557 | 0.85 | FOLH1 (0.61) | KAT6AFOLH1 | |
| SCHEMBL4958280 | 0.85 | KAT6A (0.51) | KAT6ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL991080 | 0.85 | FOLH1 (0.61) | KAT6AFOLH1 | |
| SCHEMBL8099947 | 0.84 | BCL2 (0.51) | KAT6ACYP4F2CYP4A11PLK1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |