Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27339909 | 0.84 | AKR1C3 (0.58) | AKR1C3CA1CA2BCHEACHE | |
| SCHEMBL735219 | 0.83 | AKR1C3 (0.61) | AKR1C3CA1CA2BCHEACHE | |
| P-Nitrophenol SCHEMBL7526432 | 0.82 | AKR1C3 (0.64) | AKR1C3CA1CA2BCHEACHE | |
| SCHEMBL5983483 | 0.80 | AKR1C3 (0.56) | AKR1C3CA1CA2BCHEACHE | |
| SCHEMBL915525 | 0.79 | AKR1C3 (0.59) | AKR1C3CA1CA2BCHEACHE | |
| SCHEMBL2545948 | 0.78 | CES2 (0.73) | AKR1C3CA1CA2BCHEACHE | |
| SCHEMBL1542484 | 0.78 | CA1 (0.55) | AKR1C3CA1CA2BCHEACHE | |
| SCHEMBL4989626 | 0.77 | AKR1C3 (0.53) | AKR1C3CA1CA2BCHEACHE | |
| SCHEMBL7758238 | 0.77 | TSHR (0.55) | CA1CA2BCHEACHETSHR | |
| SCHEMBL5069158 | 0.77 | AKR1C3 (1.00) | AKR1C3CA1CA2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060748-A1 | REMEDIES FOR CORNEAL EPITHELIUM DISTURBANCE | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2000-12-20 | — | — | EP | disclosed |