Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14191204 | 0.89 | LTA4H (0.70) | MTNR1AMTNR1BLTA4HCHRM2CHRM1 | |
| SCHEMBL2099512 | 0.88 | CHRM2 (0.66) | LTA4HCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL31739258 | 0.86 | LTA4H (0.67) | MTNR1AMTNR1BLTA4HCHRM2CHRM1 | |
| SCHEMBL2092574 | 0.86 | LTA4H (0.67) | MTNR1AMTNR1BLTA4HCHRM2CHRM1 | |
| SCHEMBL12497 | 0.86 | TAAR1 (0.62) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL29908907 | 0.86 | TAAR1 (0.62) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL8515510 | 0.86 | MTNR1A (0.58) | MTNR1AMTNR1BLTA4HCHRM2CHRM1 | |
| SCHEMBL13880096 | 0.85 | MAOB (0.62) | MTNR1AMTNR1BLTA4HCHRM2CHRM1 | |
| SCHEMBL27937229 | 0.84 | LTA4H (0.60) | MTNR1AMTNR1BLTA4HCHRM2CHRM1 | |
| Ammonia Solution, Strong SCHEMBL265549 | 0.84 | TAAR1 (0.60) | CHRM2CHRM1CHRM3TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |