Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22858341 | 0.89 | TAAR1 (0.62) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL156300 | 0.87 | TAAR1 (0.69) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL8093299 | 0.86 | MTNR1A (0.57) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL14191204 | 0.85 | LTA4H (0.70) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| Ammonia Solution, Strong SCHEMBL1095728 | 0.85 | TAAR1 (0.67) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL2099512 | 0.85 | CHRM2 (0.66) | CHRM2CHRM1CHRM3TAAR1LTA4H | |
| SCHEMBL31739258 | 0.83 | LTA4H (0.67) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL2092574 | 0.83 | LTA4H (0.67) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL13880096 | 0.82 | MAOB (0.62) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL27937229 | 0.81 | LTA4H (0.60) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |