Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | HEXA | P06865 | 1/20 | 0.37 |
| ▸ | HEXB | P07686 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778363 | 0.88 | NOTUM (0.46) | TP53ALDH1A1NOTUMBCL2RAPGEF4 | |
| SCHEMBL1371003 | 0.82 | TP53 (0.43) | TP53MAPTALDH1A1PKMNOTUM | |
| SCHEMBL5779452 | 0.82 | ACHE (0.44) | TP53MAPTALDH1A1HPGDNOTUM | |
| SCHEMBL5320671 | 0.81 | HSD17B10 (0.33) | TP53MAPTALDH1A1GAAHPGD | |
| SCHEMBL9794569 | 0.78 | NOTUM (0.35) | TP53MAPTALDH1A1NOTUMTSHR | |
| SCHEMBL15067982 | 0.78 | TRPA1 (0.39) | TP53MAPTALDH1A1NOTUMRAB9A | |
| SCHEMBL8088676 | 0.77 | NOTUM (0.39) | TP53MAPTALDH1A1NOTUMRAB9A | |
| SCHEMBL8081466 | 0.76 | ACHE (0.50) | TP53HPGDNOTUMACHERAB9A | |
| SCHEMBL5217872 | 0.76 | ACHE (0.50) | ACHERAB9AL3MBTL1 | |
| SCHEMBL716056 | 0.75 | TP53 (0.38) | TP53MAPTALDH1A1PKMNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |