Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193137 | 0.85 | MAOB (0.39) | ACHERAB9AHPGDNPC1TSHR | |
| SCHEMBL10658674 | 0.85 | ESR2 (0.42) | IDO1ALDH1A1 | |
| SCHEMBL8081466 | 0.85 | ACHE (0.50) | ACHERAB9AHPGDNPC1TSHR | |
| SCHEMBL2014176 | 0.85 | ACHE (0.50) | ACHERAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL4279134 | 0.85 | ACHE (0.50) | ACHEALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL5217872 | 0.85 | ACHE (0.50) | ACHERAB9ACYP3A4L3MBTL1 | |
| SCHEMBL11513961 | 0.85 | MAOA (0.44) | ACHERAB9AHPGDNPC1TSHR | |
| SCHEMBL7138582 | 0.83 | ACHE (0.36) | ACHETSHRALDH1A1 | |
| SCHEMBL8093380 | 0.82 | TP53 (0.38) | ACHERAB9AHPGDTSHRNOTUM | |
| SCHEMBL7832248 | 0.82 | ACHE (0.53) | ACHERAB9AHPGDNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030835-A1 | Derivatives of 2-substituted-6-phenyl-3(2H)pyridazinone, their production and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-06-24 | — | — | EP | claimed |
| CN-114206854-B | FXIa inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-24 | — | — | CN | disclosed |
| EP-1615890-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER-LAMBERT COMPANY (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089903-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |
| US-6777530-B1 | CROSSLINKED OLIGO- AND POLYAMINES AS SOIL RELEASE AGENTS AND ENZYME STABILIZERS IN DETERGENTS AND CLEANERS | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0036834-B1 | PROCESS FOR THE PREPARATION OF METAL COMPLEXES OF ISOINDOLINE AZINES | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | disclosed |
| EP-0036835-B1 | PROCESS FOR THE PREPARATION OF METAL COMPLEXES OF ISOINDOLINE AZINES | CIBA-GEIGY AG (CH) | 1983-09-28 | — | — | EP | disclosed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4349671-A | Process for the production of metal complexes of isoindoline azines | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| EP-0036835-A1 | Process for the preparation of metal complexes of isoindoline azines | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036834-A1 | Process for the preparation of metal complexes of isoindoline azines | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036388-A2 | Isoindoline derivatives, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |