SCHEMBL8093516

SCHEMBL8093516

O=C(Oc1cc(O)ccc1C(=O)C(O)c1ccccc1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.68
ESR2 Q92731 3/20 0.68
LMNA P02545 3/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
KMT2A Q03164 5/20 0.42
MAPT P10636 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
SLC6A3 Q01959 1/20 0.41
MEN1 O00255 4/20 0.41
USP2 O75604 2/20 0.41
GAA P10253 2/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
JAK2 O60674 1/20 0.40
ALOX15 P16050 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SERPINE1 P05121 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093513 0.85 ESR1 (0.50) ESR1ESR2LMNACES2CES1
SCHEMBL5179548 0.81 ESR1 (1.00) ESR1ESR2LMNAKMT2AMAPT
SCHEMBL9496492 0.79 ESR1 (0.64) ESR1ESR2KMT2AMAPTSMN1; SMN2
SCHEMBL28180937 0.78 CAPN1 (0.47) ESR1ESR2LMNACES2CES1
SCHEMBL7038058 0.78 MAOB (0.47) LMNACES2CES1MAPTSMN1; SMN2
SCHEMBL7615928 0.77 ESR1 (0.75) ESR1ESR2LMNAKMT2AMAPT
SCHEMBL7769810 0.77 ESR1 (0.75) ESR1ESR2LMNAKMT2AMAPT
SCHEMBL6564075 0.77 ESR1 (0.69) ESR1ESR2LMNAKMT2AMAPT
SCHEMBL8055792 0.76 MEN1 (0.54) LMNACES2CES1KMT2AMAPT
SCHEMBL30355349 0.76 MEN1 (0.54) LMNACES2CES1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053888-A1 A thermally sensitive recording paper NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-11-22 EP disclosed
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed