SCHEMBL8093513

SCHEMBL8093513

O=C(Oc1ccccc1C(=O)C(O)c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
SLC6A3 Q01959 1/20 0.49
LMNA P02545 5/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
HSD17B10 Q99714 4/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 3/20 0.43
HPGD P15428 1/20 0.43
MAPT P10636 5/20 0.43
KMT2A Q03164 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PRSS1 P07477 2/20 0.42
ACR P10323 2/20 0.42
GAA P10253 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
MEN1 O00255 1/20 0.41
JAK2 O60674 1/20 0.41
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093516 0.85 ESR1 (0.68) ESR1ESR2SLC6A3LMNACES2
SCHEMBL4846409 0.81 ESR1 (0.69) ESR1ESR2SLC6A3LMNAHSD17B10
SCHEMBL124171 0.81 LMNA (0.52) ESR1SLC6A3LMNACES2CES1
SCHEMBL30461720 0.80 SLC6A3 (0.51) ESR1ESR2SLC6A3LMNACES2
SCHEMBL16516135 0.78 LIG1 (0.54) ESR1ESR2LMNACES2CES1
SCHEMBL1428878 0.78 LMNA (0.49) ESR1SLC6A3LMNACES2CES1
SCHEMBL173919 0.78 KDM4E (0.62) ESR1LMNACES2CES1HSD17B10
SCHEMBL30682789 0.77 LMNA (0.55) ESR1LMNACES2CES1HSD17B10
SCHEMBL5162031 0.77 KMT2A (0.63) ESR1ESR2SLC6A3LMNACES2
SCHEMBL2544234 0.77 LMNA (0.77) ESR1ESR2LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053888-A1 A thermally sensitive recording paper NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-11-22 EP disclosed
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed