SCHEMBL8093644

SCHEMBL8093644

CCCCP(=O)(O)O[Si](O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.42
GABRR1 P24046 1/20 0.42
GABBR1 Q9UBS5 1/20 0.42
LPAR3 Q9UBY5 7/20 0.41
LPAR2 Q9HBW0 3/20 0.41
CETP P11597 3/20 0.39
LPAR1 Q92633 3/20 0.38
MMP2 P08253 2/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP1 P03956 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
FDPS P14324 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28932691 0.86 PPARD (0.37) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL8093639 0.80 GABBR2 (0.39) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL7025032 0.79 GABBR2 (0.39) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL5290013 0.78 GABBR2 (0.38) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL7718382 0.77 GABBR2 (0.48) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL3176756 0.75 GABBR2 (0.35) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL1455833 0.75 LPAR3 (0.54) LPAR3LPAR2CETPLPAR1
SCHEMBL28115122 0.75 GABBR2 (0.46) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL2385908 0.75
SCHEMBL7857725 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6107399-A A PROTECTIVE COATING FOR A HARD IMPERMEABLE SURFACE OFAN AQUEOUS SOLUTION OF A DIMER OF TWO TRIALKOXY SILANES, AN EMULSION OF A POLYDIORGANOSILOXANE, THE SOLUTION INCLUDING WATER AND A SOLVENT; ANTIDEPOSIT AGENTS; ANTISOILANTS; CARS DOW CORNING CORPORATION (US) 2000-08-22 US claimed
US-5209775-A Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-05-11 US claimed
CN-109276712-A The application that nanometer synzyme promotes polymer hyaluronic acid to synthesize in cell 武汉大学 2019-01-29 CN disclosed
US-6107399-A A PROTECTIVE COATING FOR A HARD IMPERMEABLE SURFACE OFAN AQUEOUS SOLUTION OF A DIMER OF TWO TRIALKOXY SILANES, AN EMULSION OF A POLYDIORGANOSILOXANE, THE SOLUTION INCLUDING WATER AND A SOLVENT; ANTIDEPOSIT AGENTS; ANTISOILANTS; CARS DOW CORNING CORPORATION (US) 2000-08-22 US disclosed
US-5900459-A Silicone release agent and method DOW CORNING CORPORATION (US) 1999-05-04 US disclosed
EP-0552874-B1 Water repellents containing organosilicon compounds DOW CORNING (US) 1998-05-06 EP disclosed
EP-0552875-B1 Water repellents containing organosilicon compounds DOW CORNING (US) 1997-08-27 EP disclosed
EP-0552874-A2 Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-07-28 EP disclosed
EP-0552875-A2 Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-07-28 EP disclosed
US-5209775-A Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-05-11 US disclosed
US-5205860-A Mixture of alkyltrioxysilane, coupling agents, and endcapped polysiloxane DOW CORNING CORPORATION (US) 1993-04-27 US disclosed