SCHEMBL8093639

SCHEMBL8093639

CCCCP(=O)(O[Si](O)(O)O)O[Si](O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.39
GABRR1 P24046 1/20 0.39
GABBR1 Q9UBS5 1/20 0.39
LPAR3 Q9UBY5 7/20 0.38
LPAR2 Q9HBW0 3/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.35
CYP3A4 P08684 1/20 0.34
LPAR1 Q92633 3/20 0.34
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28932690 0.86 PPARD (0.34) LPAR3LPAR2
SCHEMBL8093644 0.80 GABBR2 (0.42) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL17865474 0.79 GABBR2 (0.40) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL3176756 0.77 GABBR2 (0.35) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL7025029 0.76 FAAH (0.36) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL5290003 0.74 HPGD (0.35) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL2218116 0.71 LPAR3 (0.46) LPAR3LPAR2TRPM8LPAR1FAAH
SCHEMBL12815010 0.71 LPAR3 (0.46) LPAR3LPAR2TRPM8LPAR1FAAH
SCHEMBL575154 0.70 FAAH (0.48) GABBR2GABRR1GABBR1LPAR3LPAR2
SCHEMBL23466793 0.70 LPAR3 (0.45) GABBR2GABRR1GABBR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6107399-A A PROTECTIVE COATING FOR A HARD IMPERMEABLE SURFACE OFAN AQUEOUS SOLUTION OF A DIMER OF TWO TRIALKOXY SILANES, AN EMULSION OF A POLYDIORGANOSILOXANE, THE SOLUTION INCLUDING WATER AND A SOLVENT; ANTIDEPOSIT AGENTS; ANTISOILANTS; CARS DOW CORNING CORPORATION (US) 2000-08-22 US claimed
US-5209775-A Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-05-11 US claimed
US-6107399-A A PROTECTIVE COATING FOR A HARD IMPERMEABLE SURFACE OFAN AQUEOUS SOLUTION OF A DIMER OF TWO TRIALKOXY SILANES, AN EMULSION OF A POLYDIORGANOSILOXANE, THE SOLUTION INCLUDING WATER AND A SOLVENT; ANTIDEPOSIT AGENTS; ANTISOILANTS; CARS DOW CORNING CORPORATION (US) 2000-08-22 US disclosed
US-5900459-A Silicone release agent and method DOW CORNING CORPORATION (US) 1999-05-04 US disclosed
EP-0552874-B1 Water repellents containing organosilicon compounds DOW CORNING (US) 1998-05-06 EP disclosed
EP-0552875-B1 Water repellents containing organosilicon compounds DOW CORNING (US) 1997-08-27 EP disclosed
EP-0552874-A2 Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-07-28 EP disclosed
EP-0552875-A2 Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-07-28 EP disclosed
US-5209775-A Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-05-11 US disclosed
US-5205860-A Mixture of alkyltrioxysilane, coupling agents, and endcapped polysiloxane DOW CORNING CORPORATION (US) 1993-04-27 US disclosed