Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 4/20 | 0.40 |
| ▸ | FNTB | P49356 | 4/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088953 | 0.94 | FNTA (0.45) | ALOX12SMN1; SMN2ALDH1A1NPSR1USP2 | |
| SCHEMBL8101510 | 0.92 | ALOX12 (0.49) | ALOX12SMN1; SMN2ALDH1A1LMNAFNTA | |
| SCHEMBL8097860 | 0.89 | TSHR (0.48) | ALOX12CYP11B1CYP11B2ALDH1A1LMNA | |
| SCHEMBL8098288 | 0.87 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8103582 | 0.86 | ALDH1A1 (0.50) | ALOX12SMN1; SMN2ALDH1A1LMNAFNTA | |
| SCHEMBL8104384 | 0.86 | ALDH1A1 (0.50) | ALOX12SMN1; SMN2ALDH1A1LMNAFNTA | |
| SCHEMBL8105132 | 0.84 | ALDH1A1 (0.46) | CNR1ALOX12ALDH1A1FNTAFNTB | |
| SCHEMBL7513048 | 0.83 | MAPK1 (0.48) | CNR1SMN1; SMN2CYP11B1CYP11B2NPSR1 | |
| SCHEMBL5285086 | 0.83 | MAPK1 (0.48) | CNR1SMN1; SMN2CYP11B1CYP11B2NPSR1 | |
| SCHEMBL8097850 | 0.82 | FNTA (0.52) | LMNAFNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-6103487-A | DETECTING MODULATORS THAT SUPPRESS THE ACTIVITY OF A TRANSFERASES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 2000-08-15 | — | — | US | disclosed |