Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 7/20 | 0.43 |
| ▸ | FNTB | P49356 | 7/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104384 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTMEN1HTT | |
| SCHEMBL8101510 | 0.91 | ALOX12 (0.49) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8097860 | 0.90 | TSHR (0.48) | ALDH1A1LMNAKMT2AALOX12FNTA | |
| SCHEMBL8105132 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTALOX12FNTAFNTB | |
| SCHEMBL8093696 | 0.86 | CNR1 (0.44) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8088953 | 0.85 | FNTA (0.45) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL8097930 | 0.85 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8103720 | 0.85 | FNTA (0.46) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8097915 | 0.84 | FNTA (0.45) | ALOX12FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8098226 | 0.84 | FNTA (0.45) | ALOX12FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |