Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FOS | P01100 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3643724 | 0.99 | ALDH1A1 (0.47) | ALDH1A1PTGS2GAAALOX15HSD17B10 | |
| SCHEMBL17822346 | 0.82 | ALDH1A1 (0.55) | ALDH1A1PTGS2GAASMN1; SMN2TDP1 | |
| SCHEMBL17822347 | 0.82 | ALDH1A1 (0.55) | ALDH1A1PTGS2GAASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL3648031 | 0.81 | MEN1 (0.39) | ALDH1A1GAAALOX15HSD17B10FOS | |
| SCHEMBL6384400 | 0.80 | ALDH1A1 (0.61) | ALDH1A1PTGS2GAAALOX15HSD17B10 | |
| SCHEMBL8100322 | 0.80 | ALDH1A1 (0.49) | ALDH1A1PTGS2ALOX15HSD17B10FOS | |
| SCHEMBL8087359 | 0.80 | ALDH1A1 (0.49) | ALDH1A1PTGS2GAAALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL3645765 | 0.79 | ALDH1A1 (0.51) | ALDH1A1PTGS2GAAALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL3644868 | 0.79 | ALDH1A1 (0.51) | ALDH1A1PTGS2ALOX15HSD17B10FOS | |
| Hydrochloric Acid SCHEMBL3645760 | 0.79 | ALDH1A1 (0.51) | ALDH1A1PTGS2GAAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258097-B2 | Amino acid derivatives | PROXIMAGEN LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| US-8258097-B2 | Amino acid derivatives | PROXIMAGEN LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| EP-2176217-B1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20100190725-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2010-07-29 | — | — | US | disclosed |
| US-20100190725-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2010-07-29 | — | — | US | disclosed |
| WO-2009007696-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190725-A1 | AMINO ACID DERIVATIVES | NPR3, NPY4R, GFRA3 | ALDH1A1 3068/4885PTGS2 3775/4885GAA 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.