Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3644868 | 0.99 | ALDH1A1 (0.51) | ALDH1A1ALOX15FOSTTRJUN | |
| SCHEMBL6384400 | 0.85 | ALDH1A1 (0.61) | ALDH1A1ALOX15FOSTTRJUN | |
| SCHEMBL8087359 | 0.85 | ALDH1A1 (0.49) | ALDH1A1ALOX15FOSTTRJUN | |
| Hydrochloric Acid SCHEMBL3645760 | 0.84 | ALDH1A1 (0.51) | ALDH1A1ALOX15FOSTTRJUN | |
| Hydrochloric Acid SCHEMBL3645765 | 0.84 | ALDH1A1 (0.51) | ALDH1A1ALOX15FOSTTRJUN | |
| SCHEMBL8095890 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ALOX15FOSTTRJUN | |
| SCHEMBL8095808 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALOX15FOSTTRJUN | |
| Hydrochloric Acid SCHEMBL11967662 | 0.81 | ALDH1A1 (0.49) | ALDH1A1ALOX15FOSTTRJUN | |
| Hydrochloric Acid SCHEMBL3646765 | 0.81 | ALDH1A1 (0.49) | ALDH1A1ALOX15FOSTTRJUN | |
| SCHEMBL8267901 | 0.81 | RAB9A (0.54) | ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258097-B2 | Amino acid derivatives | PROXIMAGEN LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| US-8258097-B2 | Amino acid derivatives | PROXIMAGEN LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| EP-2176217-B1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20100190725-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2010-07-29 | — | — | US | disclosed |
| US-20100190725-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2010-07-29 | — | — | US | disclosed |
| WO-2009007696-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190725-A1 | AMINO ACID DERIVATIVES | NPR3, NPY4R, GFRA3 | ALDH1A1 3068/4885ALOX15 3822/4885FOS 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.