SCHEMBL8093956

SCHEMBL8093956

CC(c1ccc(Cc2ccc(N)cc2)cc1)c1ccc(Cc2ccc(N)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.64
ALDH1A1 P00352 1/20 0.64
TSHR P16473 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
CYP17A1 P05093 1/20 0.45
CYP19A1 P11511 1/20 0.45
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
GFER P55789 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.42
IDO1 P14902 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
ESR1 P03372 1/20 0.41
PDCD1 Q15116 1/20 0.41
ESR2 Q92731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093951 1.00 CYP3A4 (0.64) CYP3A4ALDH1A1TSHRTDP1CYP17A1
SCHEMBL8101702 1.00 CYP3A4 (0.64) CYP3A4ALDH1A1TSHRTDP1CYP17A1
SCHEMBL8771606 0.92 CYP3A4 (0.54) CYP3A4ALDH1A1TSHRTDP1CYP17A1
SCHEMBL14302875 0.89 ALDH1A1 (0.50) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL8099782 0.86 GFER (0.64) CYP3A4ALDH1A1TSHRTDP1CYP19A1
SCHEMBL8164161 0.85 ESR1 (0.52) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL140799 0.85 ESR1 (0.52) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL3482829 0.85 ESR1 (0.52) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL8095943 0.85 ESR1 (0.52) CYP3A4ALDH1A1TSHRTDP1GFER
SCHEMBL24114033 0.84 TSHR (0.47) CYP3A4ALDH1A1TSHRTDP1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
US-5807961-A Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element using the formers CHISSO CORPORATION (JP) 1998-09-15 US disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed