Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482829 | 1.00 | ESR1 (0.52) | ESR1PDCD1ESR2CD274MEN1 | |
| SCHEMBL8164161 | 1.00 | ESR1 (0.52) | ESR1PDCD1ESR2CD274MEN1 | |
| SCHEMBL140799 | 1.00 | ESR1 (0.52) | ESR1PDCD1ESR2CD274MEN1 | |
| SCHEMBL6659986 | 0.92 | ALDH1A1 (0.58) | ESR1PDCD1ESR2CD274MEN1 | |
| SCHEMBL20132351 | 0.89 | ACHE (0.65) | ESR1PDCD1ESR2CD274MEN1 | |
| SCHEMBL4672030 | 0.89 | TSHR (0.48) | ESR1PDCD1ESR2CD274MAPT | |
| SCHEMBL22593785 | 0.89 | ACHE (0.65) | ESR1PDCD1ESR2CD274MEN1 | |
| SCHEMBL20132340 | 0.89 | ACHE (0.65) | ESR1PDCD1ESR2CD274MEN1 | |
| Sulfamide SCHEMBL11474863 | 0.87 | CA2 (0.46) | ESR1PDCD1ESR2CD274MEN1 | |
| Sulfamide SCHEMBL11473091 | 0.87 | CA2 (0.46) | ESR1PDCD1ESR2CD274MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5807961-A | Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element using the formers | CHISSO CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0799270-A1 | POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| WO-1997014742-A1 | POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1997-04-24 | — | — | WO | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |