SCHEMBL8771606

SCHEMBL8771606

CC(c1ccc(N)cc1)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.54
ALDH1A1 P00352 1/20 0.54
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MAOB P27338 5/20 0.52
MAOA P21397 4/20 0.52
CALM1 P0DP23 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
CNR2 P34972 1/20 0.42
LTA4H P09960 1/20 0.42
SLC6A2 P23975 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CYP2A6 P11509 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093951 0.92 CYP3A4 (0.64) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL8093956 0.92 CYP3A4 (0.64) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL8101702 0.92 CYP3A4 (0.64) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL8767137 0.88 CALM1 (0.55) MAOACALM1LTA4HSLC6A2TAAR1
SCHEMBL4672030 0.83 TSHR (0.48) CYP3A4ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL8771463 0.83 CYP3A4 (0.78) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL202238 0.83 CYP3A4 (0.78) CYP3A4ALDH1A1TSHRTDP1MAOB
4,4'-Methylenedianiline SCHEMBL28946261 0.83 CYP3A4 (0.78) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL10492547 0.82 TDP1 (0.38) CYP3A4ALDH1A1TSHRTDP1MAOB
SCHEMBL14302875 0.81 ALDH1A1 (0.50) CYP3A4ALDH1A1TSHRTDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1173886-A Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element CHISSO CORP (JP) 1998-02-18 CN disclosed
EP-0799270-A1 POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1997-10-08 EP disclosed
WO-1997014742-A1 POLYAMIC ACID, POLYIMIDE FILM AND LIQUID CRYSTAL ALIGNING FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1997-04-24 WO disclosed