Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096043 | 0.99 | FOLH1 (0.42) | FOLH1BDKRB2PPARALTB4RCNR2 | |
| SCHEMBL8085934 | 0.94 | FOLH1 (0.41) | FOLH1BDKRB2PPARACNR2CYP4F2 | |
| SCHEMBL8094588 | 0.88 | FOLH1 (0.41) | FOLH1CYP4F2CYP4A11 | |
| SCHEMBL8095853 | 0.88 | FOLH1 (0.40) | FOLH1PPARALTB4RCSNK1EACE2 | |
| SCHEMBL8093908 | 0.86 | FOLH1 (0.41) | FOLH1BDKRB2PPARALTB4RCNR2 | |
| SCHEMBL8100962 | 0.82 | SLC7A5 (0.42) | FOLH1 | |
| SCHEMBL8094233 | 0.82 | FOLH1 (0.40) | FOLH1CNR2CYP4F2CYP4A11 | |
| SCHEMBL29216377 | 0.80 | OPRM1 (0.49) | CSNK1E | |
| SCHEMBL8087110 | 0.79 | LPL (0.55) | PPARACYP4F2CYP4A11 | |
| SCHEMBL8098026 | 0.79 | LPL (0.55) | PPARACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |