Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 10/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085934 | 0.91 | FOLH1 (0.41) | FOLH1SLC7A5ANPEPENPEPCYP4F2 | |
| SCHEMBL8096043 | 0.90 | FOLH1 (0.42) | FOLH1SLC7A5CYP4F2CYP4A11 | |
| SCHEMBL8093997 | 0.88 | FOLH1 (0.41) | FOLH1CYP4F2CYP4A11 | |
| SCHEMBL8100962 | 0.87 | SLC7A5 (0.42) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL8087560 | 0.86 | FOLH1 (0.40) | FOLH1SLC7A5ANPEPENPEPTAS1R3 | |
| SCHEMBL8098358 | 0.82 | FOLH1 (0.47) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL8094233 | 0.78 | FOLH1 (0.40) | FOLH1SLC7A5ANPEPENPEPCYP4F2 | |
| SCHEMBL20718631 | 0.77 | KDM4E (0.48) | — | |
| SCHEMBL8093908 | 0.77 | FOLH1 (0.41) | FOLH1SLC7A5CYP4F2CYP4A11 | |
| SCHEMBL8093173 | 0.76 | KAT6A (0.51) | FOLH1CYP4F2CYP4A11POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |