SCHEMBL196087

SCHEMBL196087

COc1ccc(C=C(CCC(C)C)C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 4/20 0.45
THRB P10828 2/20 0.45
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
GSK3B P49841 1/20 0.43
AKR1C3 P42330 1/20 0.43
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
F3 P13726 1/20 0.41
GAA P10253 1/20 0.41
RECQL P46063 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010520 0.89 LMNA (0.46) LMNATDP1MAPTTHRBKDM4E
SCHEMBL19717830 0.89 MAPT (0.48) LMNATDP1MAPTTHRBKDM4E
SCHEMBL6162547 0.87 TDP1 (0.57) LMNATDP1MAPTTHRBKDM4E
Amiloxate SCHEMBL29696497 0.86 LMNA (0.76) LMNATDP1THRBKDM4EALDH1A1
SCHEMBL8375339 0.84 TDP1 (0.66) LMNATDP1MAPTTHRBKDM4E
SCHEMBL30201502 0.83 LMNA (0.47) LMNATDP1MAPTTHRBKDM4E
SCHEMBL489474 0.83 ALOX5 (0.48) MAPTTHRBKDM4EALDH1A1NPC1
SCHEMBL8153618 0.83 NPC1 (0.59) MAPTTHRBKDM4EALDH1A1NPC1
SCHEMBL8153624 0.83 NPC1 (0.59) MAPTTHRBKDM4EALDH1A1NPC1
SCHEMBL1716809 0.83 CYP3A4 (0.54) LMNATDP1ALDH1A1AKR1C3RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3600224-B1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2026-05-06 EP claimed
US-20260108435-A1 SUNSCREEN COMPOSITION WITH FUNCTIONALIZED ZEOLITE SPF BOOSTERS SAES GETTERS S.P.A. (IT) 2026-04-23 US claimed
US-20260108436-A1 SUNSCREEN COMPOSITION WITH SPF BOOSTERS SAES GETTERS S.P.A. (IT) 2026-04-23 US claimed
EP-4518849-B1 COMPOSITION FOR TOPICAL APPLICATION FOR THE PHOTOTHERAPEUTIC TREATMENT OF INFLAMMATORY-BASED SKIN DISEASES GIULIANI SPA (IT) 2026-04-08 EP claimed
EP-4648735-B1 SUNSCREEN COMPOSITION WITH SPF BOOSTERS GETTERS SPA (IT) 2026-03-11 EP claimed
EP-4706780-A2 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS Symrise AG (DE) 2026-03-11 EP claimed
EP-4061326-B1 PERSONAL CARE COMPOSITION COMPRISING A MULTISTAGE POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-25 EP claimed
EP-4648734-B1 SUNSCREEN COMPOSITION WITH FUNCTIONALIZED ZEOLITE SPF BOOSTERS GETTERS SPA (IT) 2026-02-18 EP claimed
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof EVOLVED BY NATURE INC (US) 2026-01-15 US claimed
EP-4251121-B1 TOPICAL COMPOSITION DSM IP ASSETS BV (NL) 2025-10-01 EP claimed
EP-1324017-A2 Method to determine realistic UV protection factors or broad spectrum indexes Coty B.V. (NL) 2003-07-02 EP claimed
EP-0761201-B1 Ultraviolet radiation absorption composition ROHM & HAAS (US) 2002-01-09 EP claimed
WO-2001003663-A1 SUNSCREEN FORMULATIONS H A MILTON HOLDINGS PTY LTD (AU) 2001-01-18 WO claimed
EP-0969004-A2 2,4,6-Trianilino-1,3,5-triazine derivatives, their preparation and their use as sunscreens against UV-B sun radiations 3V SIGMA S.p.A (IT) 2000-01-05 EP claimed
EP-0834302-A1 Compositions comprising glutathione liposomes Boehringer Ingelheim Limited (GB) 1998-04-08 EP claimed
EP-0419164-B1 Hair conditioning composition UNILEVER PLC (GB) 1994-11-30 EP claimed
EP-0386898-B1 SHAMPOO COMPOSITION UNILEVER PLC (GB) 1993-09-01 EP claimed
US-5186928-A Anionic surfactant, water-insoluble sunscreen, and cationic derivative of polygalactomannan gum CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-02-16 US claimed
EP-0419164-A1 Hair conditioning composition UNILEVER PLC (GB) 1991-03-27 EP claimed
EP-0386898-A1 Shampoo composition UNILEVER PLC (GB) 1990-09-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108435-A1 SUNSCREEN COMPOSITION WITH FUNCTIONALIZED ZEOLITE SPF BOOSTERS SOD1, MCM5, GSTM1 LMNA 819/4885TDP1 3292/4885MAPT 3109/4885
US-20260014066-A1 Silk-Based Moisturizer Compositions and Methods Thereof CUTA, CD44, F12 LMNA 673/4885TDP1 3906/4885MAPT 817/4885
US-20260108436-A1 SUNSCREEN COMPOSITION WITH SPF BOOSTERS BRCA1, SQOR, NDUFB5 LMNA 2402/4885TDP1 497/4885MAPT 3653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.