SCHEMBL8094344

SCHEMBL8094344

CCc1cc(Br)c(CC)c(CC)c1CC

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
GRIA4 P48058 1/20 0.33
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
DHFR P00374 1/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168554 0.81 GRIN2D (0.36) GABRA1GABRB2NOS3NOS1NOS2
SCHEMBL27488896 0.79 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL5178615 0.78 GRIN2D (0.35) GABRA1GABRB2NOS3NOS1NOS2
Ammonia Solution, Strong SCHEMBL27455415 0.78 GRIN2D (0.35) GABRA1GABRB2NOS3NOS1NOS2
SCHEMBL10813012 0.78 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL27740004 0.76 DHFR (0.35) GABRA1GABRB2DHFR
SCHEMBL457051 0.76 ALDH1A1 (0.36) GABRA1GABRB2
Ethylene SCHEMBL27743149 0.76 GRIN2D (0.33) GABRA1GABRB2NOS3NOS1NOS2
SCHEMBL11807767 0.75 GABRA1 (0.46) GABRA1GABRB2GRIN2DGRIN3BGRIN1
SCHEMBL8090788 0.75 GABRA1 (0.42) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053990-A2 A method of producing an aromatic ketone and an aromatic ketone composition containing it TORAY INDUSTRIES, INC. (JP) 2000-11-22 EP disclosed