Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311131 | 0.76 | KMT2A (0.67) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL6480240 | 0.70 | LMNA (0.43) | MEN1KMT2AL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL4859122 | 0.69 | MEN1 (0.69) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL3236587 | 0.68 | MEN1 (1.00) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL4322660 | 0.68 | MEN1 (0.50) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL8104050 | 0.68 | SMN1; SMN2 (0.44) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL7606881 | 0.67 | MEN1 (0.43) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL8639978 | 0.67 | MEN1 (0.65) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL8639981 | 0.67 | MEN1 (0.65) | MEN1KMT2AL3MBTL1GALR3HTT | |
| SCHEMBL3667952 | 0.66 | PTGS2 (0.65) | MEN1KMT2AL3MBTL1GALR3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991654-A1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998058934-A1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-12-30 | — | — | WO | disclosed |