Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094532 | 0.85 | ENPP3 (0.36) | NR1H4 | |
| SCHEMBL11529933 | 0.70 | L3MBTL1 (0.63) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 | |
| SCHEMBL4325207 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 | |
| SCHEMBL8094542 | 0.68 | MEN1 (0.48) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 | |
| SCHEMBL4328375 | 0.67 | KMT2A (0.41) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 | |
| SCHEMBL4310719 | 0.66 | CRHBP (0.60) | SMN1; SMN2L3MBTL1KMT2AHTTALDH1A1 | |
| SCHEMBL4311131 | 0.66 | KMT2A (0.67) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 | |
| SCHEMBL4859122 | 0.66 | MEN1 (0.69) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 | |
| SCHEMBL4985798 | 0.65 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 | |
| SCHEMBL3236587 | 0.65 | MEN1 (1.00) | SMN1; SMN2L3MBTL1KMT2AMEN1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991654-A1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998058934-A1 | NOVEL 2-(IMINOMETHYL)AMINO-PHENYL DERIVATIVES, PREPARATION, APPLICATION AS MEDICINES AND COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-12-30 | — | — | WO | disclosed |