Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098416 | 0.95 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CA2TSHRHTT | |
| SCHEMBL8100828 | 0.94 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CA2POLBTSHR | |
| SCHEMBL8094464 | 0.91 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CA2POLBTSHR | |
| SCHEMBL8100398 | 0.85 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CA2POLBTSHR | |
| SCHEMBL8094022 | 0.84 | ALDH1A1 (0.40) | ALDH1A1POLBTSHRLMNAFOLH1 | |
| SCHEMBL27964130 | 0.82 | PRSS1 (0.44) | ALDH1A1TSHRLMNAFOLH1PRSS1 | |
| SCHEMBL8096208 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CA2TSHRHTT | |
| SCHEMBL15512121 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TSHRLMNAFOLH1 | |
| SCHEMBL28157803 | 0.80 | BDKRB2 (0.38) | ALDH1A1CYP3A4CA2POLBTSHR | |
| SCHEMBL8096085 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRLMNAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |