Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 10/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7764737 | 0.86 | CA2 (0.50) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL9116303 | 0.79 | CA2 (0.89) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL11789341 | 0.77 | CA2 (0.94) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL28337190 | 0.75 | CA2 (0.80) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL27345977 | 0.75 | CA2 (0.90) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL11740323 | 0.75 | CA2 (0.80) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL394354 | 0.75 | CA2 (0.89) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL12476955 | 0.75 | CA2 (0.89) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL457494 | 0.75 | CA2 (0.89) | CA2CA4CES2CES1USP2 | |
| Benzoic Acid SCHEMBL20570232 | 0.75 | CA2 (0.89) | CA2CA4CES2CES1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708809-B1 | METHOD FOR REDUCING EMISSIONS OF NOx AND PARTICULATES FROM A DIESEL ENGINE | CLEAN DIESEL TECH INC (US) | 2000-09-20 | — | — | EP | disclosed |
| EP-0668899-B1 | METHOD FOR REDUCING HARMFUL EMISSIONS FROM A DIESEL ENGINE EQUIPPED WITH A PARTICULATE TRAP | CLEAN DIESEL TECH INC (US) | 2000-09-20 | — | — | EP | disclosed |
| US-6051040-A | Method for reducing emissions of NOx and particulates from a diesel engine | CLEAN DIESEL TECHNOLOGIES, INC. (US) | 2000-04-18 | — | — | US | disclosed |
| US-6003303-A | Methods for reducing harmful emissions from a diesel engine | CLEAN DIESEL TECHNOLOGIES, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0854903-A4 | METHODS FOR REDUCING HARMFUL EMISSIONS FROM A DIESEL ENGINE | CLEAN DIESEL TECH INC (US) | 1999-04-21 | — | — | EP | disclosed |
| EP-0854903-A1 | METHODS FOR REDUCING HARMFUL EMISSIONS FROM A DIESEL ENGINE | Clean Diesel Technologies Inc. (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5749928-A | MIXING WITH FUEL ADDITIVE | PLATINUM PLUS, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997009523-A1 | METHODS FOR IMPROVING THE OPERATION OF A CATALYZED ENGINE | CLEAN DIESEL TECHNOLOGIES, INC. (US) | 1997-03-13 | — | — | WO | disclosed |
| WO-1997004045-A1 | METHODS FOR REDUCING HARMFUL EMISSIONS FROM A DIESEL ENGINE | CLEAN DIESEL TECHNOLOGIES, INC. (US) | 1997-02-06 | — | — | WO | disclosed |
| EP-0708809-A1 | METHOD FOR REDUCING EMISSIONS OF NOx AND PARTICULATES FROM A DIESEL ENGINE | PLATINUM PLUS, INC. (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002655-A1 | METHOD FOR REDUCING EMISSIONS OF NOx AND PARTICULATES FROM A DIESEL ENGINE | PLATINUM PLUS, INC. (US) | 1995-01-26 | — | — | WO | disclosed |
| WO-1994011467-A1 | METHOD FOR REDUCING HARMFUL EMISSIONS FROM A DIESEL ENGINE EQUIPPED WITH A PARTICULATE TRAP | PLATINUM PLUS, INC. (US) | 1994-05-26 | — | — | WO | disclosed |
| EP-0380134-B1 | Method for regenerating replacing or treating the catalyst in a hydroprocessing reactor | FUEL TECH NV (AN) | 1994-05-04 | — | — | EP | disclosed |
| US-5266083-A | Method for reducing pollution emissions from a diesel engine | PLATINUM PLUS, INC. (US) | 1993-11-30 | — | — | US | disclosed |
| WO-1993012207-A1 | METHOD FOR REDUCING PARTICULATE EMISSIONS FROM A DIESEL ENGINE WITH ORGANOMETALLIC PLATINUM GROUP METAL COORDINATION COMPOSITION | PLATINUM PLUS, INC. (US) | 1993-06-24 | — | — | WO | disclosed |
| US-5215652-A | Method for regenerating, replacing or treating the catalyst in a hydroprocessing reactor | PLATINUM PLUS, INC. (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0451207-A4 | METHOD FOR REDUCING EMISSIONS FROM OR INCREASING THE UTILIZABLE ENERGY OF FUEL FOR POWERING INTERNAL COMBUSTION ENGINES | — | 1991-11-06 | — | — | EP | disclosed |
| EP-0451207-A1 | METHOD FOR REDUCING EMISSIONS FROM OR INCREASING THE UTILIZABLE ENERGY OF FUEL FOR POWERING INTERNAL COMBUSTION ENGINES. | FUEL TECH INC (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0380134-A1 | Method for regenerating replacing or treating the catalyst in a hydroprocessing reactor | Fuel Tech N.V. (AN) | 1990-08-01 | — | — | EP | disclosed |
| WO-1990007561-A1 | METHOD FOR REDUCING EMISSIONS FROM OR INCREASING THE UTILIZABLE ENERGY OF FUEL FOR POWERING INTERNAL COMBUSTION ENGINES | FUEL TECH, INC. (US) | 1990-07-12 | — | — | WO | disclosed |