Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094761 | 0.89 | TSHR (0.42) | PLA2G7TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL8104179 | 0.89 | PLA2G7 (0.42) | PLA2G7TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL8438730 | 0.89 | PLA2G7 (0.45) | PLA2G7TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL8443487 | 0.88 | KMT2A (0.48) | PLA2G7TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL8094854 | 0.85 | PLA2G7 (0.39) | PLA2G7TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL8440358 | 0.83 | PLA2G7 (0.44) | PLA2G7KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL8594638 | 0.82 | PLA2G7 (0.41) | PLA2G7TSHRKDM4EALDH1A1TDP1 | |
| SCHEMBL8440280 | 0.81 | TRPV1 (0.50) | TSHRALDH1A1NAMPTKMT2ATRPV1 | |
| SCHEMBL8441268 | 0.81 | TRPV1 (0.50) | TSHRALDH1A1NAMPTKMT2ATRPV1 | |
| SCHEMBL27495124 | 0.81 | TRPV1 (0.50) | TSHRALDH1A1NAMPTKMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | claimed |
| WO-1996013484-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-09 | — | — | WO | claimed |
| US-6071899-A | Azetidinone derivatives for the treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-06-06 | — | — | US | disclosed |
| EP-0788478-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013484-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-09 | — | — | WO | disclosed |