SCHEMBL8094908

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8175170	1.00	CYP3A4 (0.47)	CYP3A4CYP2C19ACRMAOBMAOA
	SCHEMBL8183194	0.88	ABCB1 (0.55)	CYP3A4CYP2C19MAOBMAOATRPV1
	SCHEMBL5202132	0.88	ABCB1 (0.55)	CYP3A4CYP2C19MAOBMAOATRPV1
	SCHEMBL8108067	0.84	HDAC4 (0.54)	CYP3A4CYP2C19ACRMAOBMAOA
	SCHEMBL5209139	0.84	MAPT (0.51)	CYP3A4CYP2C19MAOBMAOATRPV1
	SCHEMBL8167904	0.84	MAPT (0.51)	CYP3A4CYP2C19MAOBMAOATRPV1
	SCHEMBL31341155	0.83	CYP3A4 (0.50)	CYP3A4CYP2C19ACRMAOBMAOA
	SCHEMBL8094911	0.83	NPC1 (0.67)	CYP2C19PTGS2NPC1RAB9AMAPT
	SCHEMBL8091726	0.83	PTPN1 (0.56)	PTGS2NPC1RAB9APOLBMAPT
	SCHEMBL18031147	0.81	HSD17B1 (0.59)	CYP3A4CYP2C19MAOBMAOATRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.