Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102243 | 0.88 | LMNA (0.39) | HDAC1DUSP3LMNASMN1; SMN2MAPT | |
| SCHEMBL8094946 | 0.79 | DUSP3 (0.55) | DUSP3LMNATP53MEN1KMT2A | |
| SCHEMBL8095923 | 0.77 | NPSR1 (0.53) | HDAC1DUSP3LMNASMN1; SMN2TP53 | |
| SCHEMBL8101770 | 0.76 | NPC1 (0.61) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL8093460 | 0.76 | DUSP3 (0.67) | DUSP3LMNASMN1; SMN2TP53MAPT | |
| SCHEMBL9502356 | 0.73 | MAPT (0.55) | HDAC1LMNASMN1; SMN2TP53MAPT | |
| SCHEMBL10388492 | 0.71 | HDAC1 (0.51) | HDAC1LMNASMN1; SMN2TP53MAPT | |
| SCHEMBL9771249 | 0.69 | HDAC1 (0.47) | HDAC1LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6657301 | 0.69 | ALDH1A1 (0.51) | HDAC1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL8095230 | 0.69 | DUSP3 (0.67) | DUSP3LMNASMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604657-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-12 | — | — | EP | claimed |
| EP-0604657-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-07-06 | — | — | EP | claimed |