Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 4/20 | 0.58 |
| ▸ | SCD | O00767 | 13/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094946 | 0.88 | DUSP3 (0.55) | DUSP3SCDMEN1NPC1RAB9A | |
| SCHEMBL8096406 | 0.85 | DUSP3 (0.72) | DUSP3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8100073 | 0.83 | DUSP3 (0.55) | DUSP3SCDMEN1NPC1RAB9A | |
| SCHEMBL8095230 | 0.76 | DUSP3 (0.67) | DUSP3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8102243 | 0.76 | LMNA (0.39) | DUSP3SCDMEN1NPC1RAB9A | |
| SCHEMBL8093460 | 0.74 | DUSP3 (0.67) | DUSP3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8087450 | 0.73 | MAPK1 (0.59) | DUSP3SCDMEN1NPC1RAB9A | |
| SCHEMBL3054015 | 0.72 | DUSP3 (0.76) | DUSP3SCDMEN1NPC1RAB9A | |
| SCHEMBL4932123 | 0.71 | SCD (0.82) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31243 | 0.69 | SCD (1.00) | SCDMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604657-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-12 | — | — | EP | claimed |