SCHEMBL809497

SCHEMBL809497

O=C(O)C1(C(=O)O)C=CC(C=Cc2ccccc2)=CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.38
MAPT P10636 3/20 0.38
HDAC3 O15379 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
PLIN1 O60240 2/20 0.38
LMNA P02545 2/20 0.38
RECQL P46063 2/20 0.38
PLIN5 Q00G26 2/20 0.38
ABHD5 Q8WTS1 2/20 0.38
TNKS O95271 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27447417 1.00 HDAC1 (0.38) HDAC1MAPTHDAC3HDAC4HDAC2
SCHEMBL5082374 1.00 HDAC1 (0.38) HDAC1MAPTHDAC3HDAC4HDAC2
Hydrochloric Acid SCHEMBL9546945 0.98 HDAC1 (0.37) HDAC1MAPTHDAC3HDAC4HDAC2
Alcohol SCHEMBL29274513 0.93 L3MBTL1 (0.36) HDAC1MAPTHDAC3HDAC4HDAC2
SCHEMBL9546943 0.88 HDAC1 (0.36) HDAC1MAPTHDAC3HDAC4HDAC2
SCHEMBL9003917 0.84 TTR (0.34) HDAC1MAPTHDAC3HDAC4HDAC2
SCHEMBL9639696 0.84 ALDH1A1 (0.38) HDAC1MAPTLMNAALDH1A1CYP1A2
SCHEMBL10360740 0.83 RAD51 (0.40) HDAC1MAPTHDAC3HDAC4HDAC2
SCHEMBL27570573 0.83 HDAC1 (0.37) HDAC1MAPTHDAC3HDAC4HDAC2
SCHEMBL9439999 0.81 MAPT (0.46) HDAC1MAPTHDAC3HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240227-A Cadmium-based luminescent metal organic framework material and preparation method and application thereof 江苏科技大学 2024-06-25 CN claimed
CN-117887255-B High-wear-resistance nylon composite material and preparation method thereof 苏州优利金新材料有限公司 2024-05-28 CN claimed
CN-117887255-A High-wear-resistance nylon composite material and preparation method thereof 苏州优利金新材料有限公司 2024-04-16 CN claimed
CN-116903931-A Low-precipitation calcium-zinc stabilizer and preparation method thereof 杭州朝盛塑业有限公司 2023-10-20 CN claimed
CN-115505137-B Multi-dimensional dysprosium-based single-molecule magnet based on stilbene dicarboxylic acid and preparation method thereof 晋中学院 2023-09-15 CN claimed
CN-115505137-A Multi-dimensional dysprosium-based monomolecular magnet based on stilbene dicarboxylic acid and preparation method thereof 晋中学院 2022-12-23 CN claimed
US-20220356394-A1 QUANTUM DOT MATERIAL AND PREPARATION METHOD, QUANTUM DOT LIGHT-EMITTING DIODE AND PREPARATION METHOD TCL TECHNOLOGY GROUP CORPORATION (CN) 2022-11-10 US claimed
WO-2021258690-A1 QUANTUM DOT MATERIAL AND PREPARATION METHOD, AND QUANTUM DOT LIGHT-EMITTING DIODE AND PREPARATION METHOD TCL科技集团股份有限公司 2021-12-30 WO claimed
EP-3850697-A1 POLYBENZIMIDAZOLE (PBI) MEMBRANES FOR REDOX FLOW BATTERIES University of South Carolina (US) 2021-07-21 EP claimed
WO-2020056275-A1 POLYBENZIMIDAZOLE (PBI) MEMBRANES FOR REDOX FLOW BATTERIES UNIVERSITY OF SOUTH CAROLINA (US) 2020-03-19 WO claimed
EP-0363582-A1 Substituted dioxolanes BAYER AG (DE) 1990-04-18 EP claimed
EP-0354429-A1 Substituted dioxolanes, method for their preparation and their use as pesticides BAYER AG (DE) 1990-02-14 EP claimed
EP-0337229-A2 Substituted pyri(mi)dines BAYER AG (DE) 1989-10-18 EP claimed
EP-0063747-B1 2-SUBSTITUTED OR UNSUBSTITUTED AMINOCARBONYLOXYALKYL-1,4-DIHYDROPYRIDINES BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-12-09 EP claimed
EP-0101023-B1 PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-07-29 EP claimed
EP-0097822-B1 AMINOMETHYLDIOXOLANES AS PARASITICIDES BAYER AG (DE) 1987-07-15 EP claimed
EP-0054862-B1 SUBSTITUTED DIPEPTIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE INHIBITION OF ENKEPHALINASE SCHERING CORPORATION (US) 1985-11-27 EP claimed
EP-0097822-A1 Aminomethyldioxolanes as parasiticides BAYER AG (DE) 1984-01-11 EP claimed
EP-0035244-A2 Cycloalka(4,5)pyrrolo(2,3-g)isoquinolines, processes and intermediates for their preparation, and medicines containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-09-09 EP claimed
EP-0007643-A1 Oxadiazolotriazine derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-02-06 EP claimed