Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090174 | 0.96 | F2 (0.39) | MMP8SPHK1MMEF10CYP2C19 | |
| SCHEMBL8095221 | 0.94 | MMP8 (0.41) | MMP8SPHK1MMEEPHX2F10 | |
| SCHEMBL8095146 | 0.92 | F2 (0.37) | MMP8SPHK1EPHX2L3MBTL1 | |
| SCHEMBL8091524 | 0.91 | F2 (0.37) | MMP8SPHK1EPHX2L3MBTL1 | |
| SCHEMBL8090189 | 0.90 | MMP8 (0.37) | MMP8SPHK1MMEF10PRSS1 | |
| SCHEMBL8091528 | 0.90 | F2 (0.37) | MMP8SPHK1EPHX2L3MBTL1 | |
| SCHEMBL8098087 | 0.90 | MMP8 (0.44) | MMP8MMEEPHX2CYP2D6CYP2C9 | |
| SCHEMBL8095279 | 0.89 | NPY4R (0.38) | — | |
| SCHEMBL8095448 | 0.88 | MMP8 (0.38) | MMP8SPHK1EPHX2L3MBTL1 | |
| SCHEMBL8098206 | 0.87 | C3AR1 (0.35) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |