Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095466 | 0.95 | CYP2C19 (0.39) | MMP8CYP2C19KMT2ANPC1ALDH1A1 | |
| SCHEMBL8098091 | 0.93 | MMP8 (0.43) | MMP8EPHX2MMECYP2D6CYP2C9 | |
| SCHEMBL8095266 | 0.92 | MMP1 (0.39) | MMP8CYP2C19KMT2A | |
| SCHEMBL8095211 | 0.90 | MMP8 (0.42) | MMP8EPHX2MMECYP2D6CYP2C9 | |
| SCHEMBL8095182 | 0.89 | MMP8 (0.40) | MMP8CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL8095467 | 0.88 | CYP3A4 (0.38) | MMP8CYP2C19KMT2ANPC1ALDH1A1 | |
| SCHEMBL8091668 | 0.88 | MMP8 (0.39) | MMP8L3MBTL1ALDH1A1HPGD | |
| SCHEMBL8090127 | 0.87 | KDM4E (0.36) | MMECYP2D6CYP2C19NPC1 | |
| SCHEMBL8090153 | 0.87 | MMP8 (0.40) | MMP8CYP2D6CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL8090174 | 0.86 | F2 (0.39) | MMP8MMECYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |